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Roberto Tirabosco Selected Research

Brachyury protein (Brachyury)

10/2017The driver landscape of sporadic chordoma.
11/2012An integrated functional genomics approach identifies the regulatory network directed by brachyury (T) in chordoma.
11/2011P63 does not regulate brachyury expression in human chordomas and osteosarcomas.
2/2011The role of epidermal growth factor receptor in chordoma pathogenesis: a potential therapeutic target.
2/2011Role of the transcription factor T (brachyury) in the pathogenesis of sporadic chordoma: a genetic and functional-based study.
8/2009Analysis of the fibroblastic growth factor receptor-RAS/RAF/MEK/ERK-ETS2/brachyury signalling pathway in chordomas.
4/2008Brachyury expression in extra-axial skeletal and soft tissue chordomas: a marker that distinguishes chordoma from mixed tumor/myoepithelioma/parachordoma in soft tissue.
1/2007Diagnosing an extra-axial chordoma of the proximal tibia with the help of brachyury, a molecule required for notochordal differentiation.

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Roberto Tirabosco Research Topics

Disease

18Neoplasms (Cancer)
12/2020 - 04/2007
10Chordoma
01/2020 - 01/2007
9Osteosarcoma (Osteogenic Sarcoma)
01/2020 - 11/2011
5Chondrosarcoma
12/2021 - 04/2008
4Sarcoma (Soft Tissue Sarcoma)
07/2021 - 04/2008
3Pain (Aches)
01/2018 - 02/2011
3Chondroblastoma
07/2016 - 12/2013
2Neurofibrosarcoma (MPNST)
10/2020 - 01/2018
2Osteoblastoma
12/2019 - 07/2017
2Fibroma (Fibromatosis)
08/2015 - 09/2014
2Glioma (Gliomas)
01/2013 - 07/2011
1Soft Tissue Neoplasms
07/2021
1Aneuploidy (Aneuploid)
12/2020
1Necrosis
10/2020
1Monosomy
01/2020
1Chondroma (Enchondroma)
12/2019
1Synovial Chondromatosis (Synovial Osteochondromatosis)
12/2019
1Osteoid Osteoma
12/2019
1Ossifying Fibroma
01/2019
1Neurofibroma
01/2018
1Fever (Fevers)
10/2017
1Fatigue
10/2017
1Disease Progression
10/2017
1Neutropenia
10/2017
1Febrile Neutropenia
10/2017
1Stomatitis
10/2017
1Giant Cell Tumor of Bone
08/2017
1Clear Cell Chondrosarcoma
07/2016
1Urinary Bladder Neoplasms (Bladder Cancer)
12/2015
1Aggressive Fibromatosis (Desmoid)
08/2015
1Brain Neoplasms (Brain Tumor)
12/2013
1Giant Cell Tumors (Giant Cell Tumor)
12/2013
1Bone Diseases (Bone Disease)
04/2013
1Spontaneous Fractures (Pathological Fracture)
04/2013
1Cholangiocarcinoma
01/2013
1Lipoblastoma
10/2012
1Lipoma (Lipomata)
10/2012
1Liposarcoma
10/2012
1Proteus Syndrome
08/2011
1Hemangioma (Angioma)
02/2011

Drug/Important Bio-Agent (IBA)

8Transcription Factors (Transcription Factor)IBA
01/2018 - 01/2007
8Brachyury protein (Brachyury)IBA
10/2017 - 01/2007
6DNA (Deoxyribonucleic Acid)IBA
12/2021 - 02/2011
6Proteins (Proteins, Gene)FDA Link
01/2020 - 01/2008
5Phosphotransferases (Kinase)IBA
01/2019 - 08/2011
5ParaffinIBA
10/2015 - 04/2007
4Biomarkers (Surrogate Marker)IBA
12/2021 - 08/2014
4Formaldehyde (Formol)FDA Link
10/2020 - 04/2007
4Histones (Histone)IBA
10/2020 - 12/2013
4Isocitrate Dehydrogenase (Isocitrate Dehydrogenase (NAD+))IBA
02/2015 - 07/2011
2A-Form DNA (A-DNA)IBA
07/2021 - 01/2013
2Growth Factor ReceptorsIBA
08/2014 - 08/2009
2EnzymesIBA
08/2011 - 05/2009
1Cyclin D1IBA
12/2020
1Prednisolone (Predate)FDA LinkGeneric
12/2020
1Lysine (L-Lysine)FDA Link
10/2020
1Polycomb Repressive Complex 2IBA
10/2020
1Type 2 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 2)IBA
12/2019
1Fibronectins (Fibronectin)IBA
12/2019
1Activin Receptors (Activin Receptor)IBA
12/2019
1AntibodiesIBA
12/2019
1Fibroblast Growth Factor-23IBA
12/2019
1RNA (Ribonucleic Acid)IBA
12/2019
1Messenger RNA (mRNA)IBA
12/2019
1Atrial Natriuretic Factor (ANF)IBA
01/2018
1Interleukin-33IBA
01/2018
1Doxorubicin (Adriamycin)FDA LinkGeneric
10/2017
1Circulating Tumor DNAIBA
10/2017
1GemcitabineFDA Link
10/2017
1Docetaxel (Taxotere)FDA Link
10/2017
1Monoclonal AntibodiesIBA
08/2017
1Sirtuin 1IBA
07/2017
1cyclo(Arg-Pro) (CI 4)IBA
12/2015
1beta CateninIBA
08/2015
1Class 3 Receptor-Like Protein Tyrosine PhosphatasesIBA
04/2014
1Tyrosine (L-Tyrosine)FDA Link
04/2014
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
04/2014
1Biological ProductsIBA
07/2013
1Diphosphonates (Bisphosphonates)IBA
04/2013
1Retinoic Acid Receptors (Retinoic Acid Receptor)IBA
01/2013
1ChromatinIBA
01/2013
1NucleotidesIBA
11/2012
1Dihydrotachysterol (AT 10)IBA
10/2012
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
02/2011
1Interleukin-2 Receptors (IL 2 Receptor)IBA
02/2011
1RTKI cpdIBA
02/2011
1ErbB Receptors (EGF Receptor)IBA
02/2011
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
08/2009
1Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
08/2009
1Codon (Codons)IBA
08/2009
1MART-1 AntigenIBA
06/2009
1S100 Proteins (S 100 Protein)IBA
06/2009

Therapy/Procedure

4Drug Therapy (Chemotherapy)
10/2020 - 02/2011
1Neoadjuvant Therapy
10/2020
1Curettage
09/2014
1Adjuvant Chemotherapy
08/2014
1Therapeutics
08/2014
1Radiotherapy
04/2013
1Hip Replacement Arthroplasty (Total Hip Replacement)
02/2011
1Arthroplasty
02/2011